We introduce the first comprehensive catalog of the hard binary population studied in the rich open cluster NGC 7789 (1.6 Gyr, [Fe/H] = +0.02). Our sample consists of 1206 photometrically selected stars drawn from the upper main sequence and evolved stellar population of NGC 7789, which includes giants, red-clump stars, blue stragglers, red stragglers, and sub-subgiants. Our survey, as part of the ongoing WIYN Open Cluster Study (WOCS), began in 2005 and comprises more than 9,000 time-series radial-velocity measurements from the Hydra Multi-Object Spectrograph on the WIYN 3.5m telescope. We derive RV membership probabilities, and in conjunction with high-precision astrometry obtained from Gaia DR2, we are able to identify 564 likely cluster members and fit orbital solutions for 83 cluster binary stars with periods between 1.45 d and 4200 d, including four blue stragglers. From this catalog we investigate key cluster properties such as binary frequency and tidal circularization period. These data are a foundation for future dynamical studies of intermediate-age, densely populated open clusters such as NGC 7789. The authors acknowledge funding support from NSF AST-1714506. The authors also gratefully acknowledge the many Wisconsin undergraduate and graduate students who have contributed to the WIYN Open Cluster Study radial-velocity database.